Cor et Vasa - Latest articles

Relationship between Functional Capacity and Medication Adherence in Heart FailureOriginal research articles

Libor Jelínek, Martin Modrák, Zdeněk Ramík, Lukáš Štos, Luděk Pavlů, Jan Václavík, Eliška Sovová

Cor Vasa 2023, 65(Suppl. 3):37-43 | DOI: 10.33678/cor.2023.064  

Introduction: This study investigated the relationship between the subjective New York Heart Association (NYHA) class and objective exercise capacity (VO_2peak) in patients with heart failure and whether it is influenced by medication adherence. Methods: Data from 170 heart failure patients in the Level-CHF register were analysed, and adherence was assessed by serum drug level testing. Objective exercise capacity was assessed by cardiopulmonary exercise testing using a bicycle ergometer. Results: Objective VO_2peak frequently exceeded the subjective NYHA class with 46% concordance, especially at the extreme ends of the spectrum....

Pulmonary edema in swimmers and diversReview articles

Radek Pudil

Cor Vasa 2023, 65(Suppl. 3):34-36 | DOI: 10.33678/cor.2023.076  

Pulmonary edema in swimmers and divers is defined as sudden onset of shortness of breath accompanied by cough, hemoptysis, and hypoxemia that occurs in association with increased physical activity, especially in a water/cold environment. It occurs more often in women and in the elderly, predisposing factors include a cold environment and the presence of some latent cardiovascular diseases. It is a potentially life-threaten- ing condition for athletes. Its therapy does not differ from the treatment of pulmonary cardiac edema. Early identification of persons with a higher risk and elimination of all potentially risk factors for its occurrence is very...

(Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology. Translation of the document prepared by the Czech Society of Cardiology)Expert consensus statement

Vladimír Tuka, Eliška Sovová, Radek Pudil, Hana Skalická

Cor Vasa 2023, 65(Suppl. 3):5-33 | DOI: 10.33678/cor.2023.060  

Secondary prevention through comprehensive cardiac rehabilitation has been recognized as the most cost-effective intervention to ensure favourable outcomes across a wide spectrum of cardiovascular disease, reducing cardiovascular mortality, morbidity and disability, and to increase quality of life. The delivery of a comprehensive and 'modern' cardiac rehabilitation programme is mandatory both in the residential and the out-patient setting to ensure expected outcomes. The present position paper aims to update the practical recommendations on the core components and goals of cardiac rehabilitation intervention in different cardiovascular conditions,...

Jiří Vítovec, Peter Kollár, Karel Lábr: Betablokátory v léčbě kardiovaskulárních onemocněníBook reviews

Prof. MUDr. Michael Aschermann, DrSc.

Cor Vasa 2023, 65(Suppl. 1):76  

(Antithrombotic therapy in older patients)Editorial

Petr Ošťádal, Miloš Táborský, Zuzana Moťovská

Cor Vasa 2023, 65(Suppl. 1):6 | DOI: 10.33678/cor.2023.037  

(2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation. Translation of the document prepared by the Czech Society of Cardiology)Expert consensus statement

Miloš Táborský, Josef Kautzner, Marián Fedorco, Karol Čurila, Hanka Wünschová, Jan Pyszko, Miroslav Novák, Milan Kozák, Martin Válek, Rostislav Polášek, Patrik Keprt, Milena Kubíčková, Jiří Plášek, Vít Gloger, Alan Bulava, Vlastimil Vančura, Tomáš Skála, Petr Pařízek, Josef Daněk

Cor Vasa 2023, 65(Suppl. 1):23-75 | DOI: 10.33678/cor.2023.024

(Acute, periprocedural and longterm antithrombotic therapy in older adults: 2022 Update by the ESC Working Group on Thrombosis. Translation of the document prepared by the Czech Society of Cardiology)Expert consensus statement

Miloš Táborský, Zuzana Moťovská, Petr Ošťádal

Cor Vasa 2023, 65(Suppl. 1):7-22 | DOI: 10.33678/cor.2023.012

The fi rst international guidance on antithrombotic therapy in the elderly came from the European Society of Cardiology Working Group on Thrombosis in 2015. This same group has updated its previous report on antiplatelet and anticoagulant drugs for older patients with acute or chronic coronary syndromes, atrial fi brillation, or undergoing surgery or procedures typical of the elderly (transcatheter aortic valve implantationand left atrial appendage closure). The aim is to provide a succinct but comprehensive tool for readers to understand the bases of antithrombotic therapy in older patients, despite the complexities of comorbidities, comedications...

Opustil nás pan profesor MUDr. Bohumil Hučín, DrSc.Personalities

Michael Aschermann

Cor Vasa 2023, 65(6):893-894  

Zemřel profesor MUDr. Bohumil Hučín, DrSc.Personalities

Prof. MUDr. Tomáš Tláskal, CSc.

Cor Vasa 2023, 65(6):893-894  

21. konference České asociace akutní kardiologie - AbstraktaAbstracts

redakce

Cor Vasa 2023, 65(6):897-908  

Petr Bartůněk: Eponyma v medicíně aneb po kom to slovo jeBook reviews

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2023, 65(6):896  

Profesorka MUDr. Zuzana Moťovská, Ph.D., získala cenu vlády ČR – Česká hlavaCurrent news

Michael Aschermann

Cor Vasa 2023, 65(6):895  

Profesor MUDr. Vladimír Staněk, CSc., FESC, získal státní vyznamenáníCurrent news

Michael Aschermann

Cor Vasa 2023, 65(6):895  

(European Health Data Space (EHDS) in the context of the digital transformation of cardiology and systemic changes of the health system in the Czech Republic)Expert consensus statement

Miloš Táborský, Lenka Kaška, Jiří Horecký, Jiří Batěk, Michal Vrablík, Aleš Linhart, Petr Ošťádal

Cor Vasa 2023, 65(6):880-891 | DOI: 10.33678/cor.2023.088  

Coronary evagination after self-apposing stent deployment: a rare but possible event. A clinical case at 4-year follow-upCase reports

Giuseppe Venuti, Francesca Consolo, Claudia Morabito, Alice Moncada, Olga La Cognata, Rosalba De Sarro, Alessandro Di Carlo, Armando Lo Savio, Marco Cerrito

Cor Vasa 2023, 65(6):877-879 | DOI: 10.33678/cor.2023.021  

Background: Coronary evagination is a coronary abnormality that has been associated with poor long-term outcomes irrespective of the presence of concomitant coronary artery disease (CAD). Its pathogenesis is still not well understood; intracoronary manipulation and percutaneous coronary intervention (PCI) are considered predictors of coronary enlargement through mechanism such as prolonged inflammation, suboptimal endothelialization and vessel positive remodeling. Some stent platforms, like self-apposing stents, seem to be more involved, causing more vessel remodeling. Case presentation: We report the case of a 79-year-old woman who underwent percutaneous...

Aspirin-induced Anaphylactoid Reactions in a Patient with Acute Coronary Syndrome Complicating Acute Lung Edema: a Case ReportCase reports

Meity Ardiana, Kevin Francio, Inna Maya Sufiyah, Fita Triastuti, Muhammad Nuh Hamdani

Cor Vasa 2023, 65(6):874-876 | DOI: 10.33678/cor.2023.028  

Background: Antiplatelet therapy is an essential treatment for patients with acute coronary syndrome. But a history of aspirin hypersensitivity has been reported and it might be challenging to treat a patient with this case. Case: A 65-year-old Javanese woman came to the emergency department and presented with dyspnea for three days and with orthopnea. Based on physical and supporting examination, the patient was diagnosed with ADHF. However, on the 3rd day of treatment, ECG showed new T wave inversion at lead V₁ to V₆, I, and aVL lead to NSTEACS. Loading doses of antiplatelets (clopidogrel and aspirin) were administered. Three...

An Experimental Case-Based Role Model Study of Mitral NeoChord Implantation with New Tools via Transapical ApproachCase reports

Ersin Doganozu, Ayşe Ceren Doganozu, Deniz Sarp Beyazpinar, Atilla Sezgin, Ibrahim Haldun Muderrisoglu, Alp Aydinalp

Cor Vasa 2023, 65(6):870-873 | DOI: 10.33678/cor.2023.044  

Increasing fragility with the aging population compels less invasive procedures. Even if cardiac surgeries are getting minimally invasive with new techniques and technological development in the field, many valve surgery candidates suffer from being qualified as inoperable due to fragility, unstable circulatory system, and to be post-myocardial infarction and their life is in danger every day that they are not operated. The main purpose of this case-based role model study is to invent a new technique for implanting a transapical mitral valve NeoChord implantation with new tools.

Surgical treatment of large aortic pseudoaneurysm in a 17-year-old patient: a case reportCase reports

Fadi Sabateen, Matej Nosáľ, Vladimír Soják, Aref Seif Nagi, Pavel Valentík, Michal Šagát

Cor Vasa 2023, 65(6):866-869 | DOI: 10.33678/cor.2023.049  

Aortic pseudoaneurysms are rare, but life-threatening conditions, that occur most commonly after previous cardiac surgery. The causes could be multifactorial such as chest trauma or infection. Clinical presentation can vary from asymptomatic to catastrophic outcomes. We report the successful surgical repair of a large ascending aortic pseudoaneurysm in an asymptomatic 17-year-old patient who had undergone aortic valve replacement 10 months ago.

Surgical treatment of aortic pseudoaneurysm after endovascular repairCase reports

Sandra Rečičárová, Michael Jonák

Cor Vasa 2023, 65(6):862-864 | DOI: 10.33678/cor.2023.062  

Thoracic aortic false aneurysm (TAFA) is a rare complication after cardiac surgery or after procedures on the thoracic aorta. We present a case report of a patient after Bentall's procedure for aortic dissection who developed an aortic pseudoaneurysm in distal anastomosis one year after surgery. Endovascular repair with occluder implantation was successfully performed. Three years later another false aneurysm from the left coronary artery occurred which had to be resected in open surgery.

Role of Corin in Cardiovascular DiseaseReview articles

Lutfu Askin, Fatih Poyraz

Cor Vasa 2023, 65(6):856-861 | DOI: 10.33678/cor.2023.055  

Corin, a type II transmembrane serine protease present in significant amounts in the heart, activates natri-uretic peptides. Corin enters the circulation from myocytes. Hypertension, heart failure, myocardial infarction, preeclampsia, and stroke are linked to circulating soluble corin. Our results suggest that circulating soluble corin may be a sensitive and specific cardiovascular disease (CVD) risk and predictive biomarker. Unfortunately, circulating soluble corin is difficult to use clinically. This review summarizes recent corin and CVD studies and suggests future corin research to improve risk prediction, prognosis, and medical treatment of CVDs...

(The effect of an inter-atrial communication in the treatment of the patients with heart failure with mildly reduced and preserved ejection fraction - current state of knowledge)Review articles

Filip Málek, Martin Mates, Tomáš Mráz, Vivek Reddy, Andreas Krüger, Petr Neužil

Cor Vasa 2023, 65(6):849-854 | DOI: 10.33678/cor.2023.068  

An elevated left atrial pressure at rest and especially at stress is the main cause of symptoms and an increased risk of hospitalization and death in patients with heart failure. The mechanistic approach with implantation of inter-atrial shunt device (IASD) to reduce left atrial pressure in the patients with heart failure with mildly reduced and preserved ejection fraction was feasible and safe in a pilot study. In a non-randomized REDUCE LAP-HF and a randomized REDUCE LAP-HF I study the implantation of IASD was associated with improved symptoms and hemodynamic parameters. The effect of IASD on the risk of cardiovascular events including death and...

DNA methylation and coronary artery disease: Brief summary of the main findingsReview articles

Asma Amrani-Midoun, Nadia Laredj, Farouk Boukerche

Cor Vasa 2023, 65(6):843-847 | DOI: 10.33678/cor.2023.067  

Cardiovascular disease (CVD) and more specifically coronary artery disease (CAD) continue to be the leading cause of mortality worldwide. Many genetic factors have been identified to contribute to the risk of develop-ing CAD. However, the etiology and pathophysiology of complex diseases such as CAD are driven not only by genetic factors but also by the interaction between genetic and environmental factors. Therefore, research-ers are now exploring the epigenome, a biological interface at which genetics and the environment can interact. DNA methylation is the main epigenetic form of gene regulation, and it is increasingly recognized to play an important...

Pulmonary Hemodynamics in Patients with Chronic Kidney Disease before Starting Renal Replacement TherapyOriginal research articles

Fouad Bekhit, Yasser Baghdady, Noha Hassanin, Huessin Elfishawi, Karim Said

Cor Vasa 2023, 65(6):837-842 | DOI: 10.33678/cor.2023.083  

Background: Pulmonary hypertension (PH) is a highly prevalent condition in patients with chronic kidney disease and is associated with worse outcomes. Many studies described the prevalence of PH in patients with chronic renal disease on established renal replacement therapy (RRT) by non-invasive methods. However, there is a paucity of data on the peculiar hemodynamic characterization of patients with CKD prior to estab-lished RRT. Purpose: Our study aimed to describe the pulmonary hemodynamics in chronic kidney disease patients before starting established renal replacement therapy by invasive cardiac catheterization. Methods: A total of ninety-five...

Clinical and Demographic Properties of Candida Endocarditis in a Tertiary Heart CenterOriginal research articles

Sibel Doğan Kaya, Yeşim Uygun Kizmaz

Cor Vasa 2023, 65(6):832-835 | DOI: 10.33678/cor.2023.063  

Background: Candida is a rare but important cause of infective endocarditis. The study aimed to describe clinical data on patients with Candida endocarditis treated in cardiology and cardiovascular surgery hospital between 2012-2023. Methods: Patients diagnosed with infective endocarditis were reviewed retrospectively. Demographic information, medical histories, clinical data, and information on outcome and treatment were presented. Results: Four (29%) of 14 patients were female, and 10 (71%) were male. The mean age was 49.7 (±8.82) years. The mean hospital stay was 39 days (33-130 days). The valves involved were 5 (38%) aortic valves,...

(Inclisiran - the first experiences)Original research articles

Michaela Štroffeková, Jana Obrová, Miloš Táborský

Cor Vasa 2023, 65(6):827-831 | DOI: 10.33678/cor.2023.066  

We present our first experience with the use of new parenteral hypolipidemic therapy in clinical practice. Our set of patients was started on hypolipidemic therapy with inclisiran and was followed by measuring the lipid spectrum parameters from December 2021 to March 2023. During this follow-up, hypolipidemic therapy with inclisiran proved to be effective and safe with good adherence to therapy.

Long-stay predictors in the intensive care unit after Bentall procedure: retrospective researchOriginal research articles

Viktoriia Tymoshenko, Oleh Zelenchuk, Stepan Maruniak, Serhii Sudakevych, Vitalii Demyanchuk, Borys Todurov

Cor Vasa 2023, 65(6):821-825 | DOI: 10.33678/cor.2023.071  

Aim: To analyze the frequency of early postoperative complications and predictors of long-stay patients in the intensive care unit (ICU) after the Bentall procedure. Materials and methods: This retrospective study is based on the obtained medical records of adult patients (aged 18-75), who underwent Bentall procedure for an ascending aortic aneurysm between 2012 and 2021. Depending on the length of ICU stay, all patients were divided into two groups: length of ICU stay up to 3 days (group 1) and length of ICU stay longer than 3 days (group 2). Univariate and multivariate analysis (logistic regression) was used to determine prognostic risk factors....

(The effect of listening to reproduced music on the assessment of fear in patients before heart surgery)Original research articles

Eva Baudyšová, Darja Jarošová, Renáta Zeleníková

Cor Vasa 2023, 65(6):814-820 | DOI: 10.33678/cor.2023.052  

Aim: The aim of the intervention study was to determine the effect of listening to recorded music on the assessment of fear in patients before heart surgery. Methods: The target population were men with planned heart surgery. An intervention study was conducted in (May-December) 2022 in the inpatient department of the cardiocenter. The set of patients was randomly divided into two groups. In the intervention group, in addition to the standard care before the operation, the intervention of listening to recorded music was implemented (30 min, 1 meeting, selection from 10 genres). The control group received standard care before surgery (education about...

Kazuistické číslo Cor et Vasa podesátéEditorial

Michael Aschermann

Cor Vasa 2023, 65(5):728 | DOI: 10.33678/cor.2023.077  

EditorialEditorial

Petr Ošťádal

Cor Vasa 2023, 65(5):727 | DOI: 10.33678/cor.2023.078  

Tim Harford: Jak číst čísla. Deset pravidel pro orientaci ve statistikáchBook reviews

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2023, 65(5):808