Cor Vasa 2023, 65(2):181-185 | DOI: 10.33678/cor.2022.120

(Multisystem inflammatory syndrome in adults in cardiology intensive care unit, brief summary and case report)

Martin Vojtíšek^a, Nedal Omran^a, Tereza Špornová^a, Pavel Červinka^{a, b}

^a Klinika kardiologie, Krajská zdravotní a.s., Masarykova nemocnice v Ústí nad Labem, o.z., Ústí nad Labem

^b Univerzita Jana Evangelisty Purkyně v Ústí nad Labem, Ústí nad Labem

Background: As a part of world-wide spreading COVID-19 disease pandemic, a life-threatening syndrome affecting predominantly young adults was discovered. This entity usually occurs within 4 weeks after the onset of SARS-CoV-2 infection. The disease is often associated with several organ involvements, including the heart. This newly emerging unit is known as multisystem inflammatory syndrome in adults (MIS-A). Case presentation: We describe a case of a 29-year-old patient with MIS-A with predominant cardiac involvement. At admission the patient experienced fever and signs of acute left-sided heart failure, which was thought to be associated with recent SARS-CoV-2 infection as MIS-A. The patient was treated with immunomodulation therapy including methylprednisolone and intravenous immunoglobulins with prompt improvement of patient's condition and rapid normalization of the left ventricular ejection fraction.

Keywords: Coronavirus, COVID-19, Heart failure, Hyperinflammation, Multisystem inflammatory syndrome

Received: November 8, 2022; Revised: November 8, 2022; Accepted: November 11, 2022; Published: May 1, 2023  Show citation