Cor Vasa 2021, 63(6):720-724 | DOI: 10.33678/cor.2021.050

(Carcinoid heart disease in a patient with primary ovarian carcinoid)

Eva Kapsováa, Jan Václavíka, Tomáš Veisera, Patricie Delongováb
a Oddělení kardiovaskulární, Interní a kardiologická klinika, Fakultní nemocnice Ostrava, Ostrava
b Ústav patologie, Fakultní nemocnice Ostrava, Ostrava

Carcinoid heart disease is a collective term for all heart diseases that result from the action of neurohumoral substances produced by carcinoids. In most cases, it is a dysfunction of right-sided heart valves, predominantly the tricuspid valve’s insuffi ciency, leading to right heart failure. A small proportion of patients, up to approximately 10%, may also affect the mitral and aortic valves. In the case report, we present a patient diagnosed with a rare primary ovarian carcinoid, clinically present carcinoid syndrome, including both rightand left-sided heart valve involvement and rapid clinical progression of the disease.

Keywords: Carcinoid heart disease, Ovarian carcinoid, Tricuspid valve insuffi ciency

Received: April 3, 2021; Revised: April 3, 2021; Accepted: April 7, 2021; Published: December 13, 2021  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Kapsová E, Václavík J, Veiser T, Delongová P. (Carcinoid heart disease in a patient with primary ovarian carcinoid). Cor Vasa. 2021;63(6):720-724. doi: 10.33678/cor.2021.050.
Download citation

Attachments

Download filekarcinoid-video.avi

File size: 8.03 MB

References

  1. Sedláčková E, Bajčiová V, a kolektiv. Neuroendokrinní nádor. Praha: Maxdorf Jessenius, 2016:373.
  2. Gade AK, Olariu E, Douthit NT. Carcinoid Syndrome: A Review. Cureus 2020;12:7186. Go to original source... Go to PubMed...
  3. Barkmanová J. Karcionoidy. Onkologie 2016;3:336-342.
  4. Ram P, Penalver JL, Lo KBU, et al. Carcinoid Heart Disease: Review of Current Knowledge. Texas Heart Institute J 2019;46:21-27. Go to original source... Go to PubMed...
  5. Talerman A. Germ cell tumors of the ovary. Curr Opin Obstet Gynecol 1997;9:44-47. Go to original source...
  6. Kolouch T, Linkova H, Lang O, et al. Carcinoid Heart Disease in a Primary Ovarian Carcinoid. Acta Cardiol Sin 2016;32:112-115.
  7. Metwally IH, Elalfy AF, Awny S, et al. Primary ovarian carcinoid: A report of two cases and a decade registry. J Egypt Natl Canc Inst 2016;28:267-275. Go to original source... Go to PubMed...
  8. Roberts WC, Varughese CA, Ko JM, et al. Carcinoid heart disease without the carcinoid syndrome but withquadrivalvular regurgitation and unsuccessful operative intervention. Am J Cardiol 2011;107:788-792. Go to original source... Go to PubMed...
  9. Tadokoro T, Katsuki S, Ito K, et al. Inoperable Primary Ovarian Carcinoid Led to the Progression of Carcinoid Heart Disease From Right-Sided to Both-Sided Involvement. Circ Heart Fail 2017;10:3719. Go to original source... Go to PubMed...
  10. Yuan SM. Valvular Disorders in Carcinoid Heart Disease. Braz J Carciovasc Surg 2016;31:400-405. Go to original source... Go to PubMed...
  11. Pellikka PA, Tajik AJ, Khandheria BK, et al. Carcinoid heart disease: Clinical and echocardiographic spectrum in 74 patients. Circulation 1993;87:1188-1196. Go to original source... Go to PubMed...
  12. Bhattacharyya S, Toumpanakis C, Burke M, et al. Features of carcinoid heart disease identified by 2- and 3-dimensional echocardiography and cardiac MRI. Circ Cardiovasc Imaging 2010;3:103-111. Go to original source... Go to PubMed...
  13. Zuetenhorst JM, Bonfrer JM, Korse CM, et al. Carcinoid heart disease: the role of urinary 5-hydroxyindoleacetic acid excretion and plasma levels of atrial natriuretic peptide, transforming growth factor-beta and fibroblast growth factor. Cancer 2003;97:1609-1615. Go to original source... Go to PubMed...
  14. Zuetenhorst JM, Korse CM, Bonfrer JM, et al. Role of natriuretic peptides in the diagnosis and treatment of patients with carcinoid heart disease. Br J Cancer 2004;90:2073-2079. Go to original source... Go to PubMed...
  15. Fox DJ, Khattar RS. Carcinoid heart disease: presentation, diagnosis, and management. Heart 2004;90:1224-1228. Go to original source... Go to PubMed...

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.





Cor et Vasa

You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.