Cor Vasa 2021, 63(5):588-591 | DOI: 10.33678/cor.2021.001

An "ordinary" case of COVID-19 pneumonia: when symptoms hide serious complications

Francesco Messinaa, Marianna Gigliotti De Faziob, Claudia Morabitob, Roberto Licordarib, Cristina Procopio Mariab, Maurizio Mezzettic, Paolo Busaccac, Giuseppe Dattilob, Nicola Arcadia, Matteo Casalec
a Operative Unit of Radiology - G.O.M. Bianchi Melacrino Morelli, Reggio Calabria, Italy
b Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy
c Hospital "S. Maria della Misericordia", Operative Unit of ICCU and Cardiology, ASUR Marche-Area Vasta 1, Urbino, Italy

COVID-19 pandemic changed quickly world's clinical picture. Symptoms often are sneaky, hiding dramatic clinical scenarios. A 52-year-old man was sent to the Emergency Department with persistent chest pain, dyspnea and hypoxia. He also complained of cough and fever (38 °C) since four days without clinical improvements by paracetamol. Nasopharyngeal swab was positive for SARS-CoV-2. High resolution computer tomography (HRCT) showed typical CT pattern of bilateral COVID-19 pneumonia. During hospital stay clinical worsening occurred and a CT pulmonary angiography revealed a bilateral massive acute pulmonary embolism. The patient was treated with unfractionated heparin.

Keywords: Chest computed tomography, COVID-19, Low molecular weight heparin, Pulmonary embolism, SARS-CoV-2

Received: December 6, 2020; Revised: December 6, 2020; Accepted: January 2, 2021; Published: October 20, 2021  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Messina F, De Fazio MG, Morabito C, Licordari R, Maria CP, Mezzetti M, et al.. An "ordinary" case of COVID-19 pneumonia: when symptoms hide serious complications. Cor Vasa. 2021;63(5):588-591. doi: 10.33678/cor.2021.001.
Download citation

References

  1. Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020;323:1061-1069. Go to original source... Go to PubMed...
  2. Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology 2020;296:E32-E40. Go to original source... Go to PubMed...
  3. Xie X, Zhong Z, Zhao W, et al. Chest CT for Typical Coronavirus Disease 2019 (COVID-19) Pneumonia: Relationship to Negative RT-PCR Testing. Radiology 2020;296:E41-E45. Go to original source... Go to PubMed...
  4. Zhai Z, Li C, Chen Y, et al. Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Infection: A Consensus Statement before Guidelines. Thromb Haemost 2020;120:937-948. Go to original source... Go to PubMed...
  5. Cui S, Chen S, Li X, et al. Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia. J Thromb Haemost 2020;18:1421-1424. Go to original source... Go to PubMed...
  6. Thachil J, Tang N, Gando S, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. J Thromb Haemost 2020;18:1023-1026. Go to original source... Go to PubMed...
  7. Iba T, Levy JH, Levi M, et al. Coagulopathy of Coronavirus Disease 2019. Crit Care Med 2020;48:1358-1364. Go to original source... Go to PubMed...
  8. Casale M, Dattilo G, Imbalzano E, et al. The thromboembolism in COVID-19: the unsolved problem. Panminerva Med. 2020 Jun 16. doi: 10.23736/S0031-0808.20.03999-3. Epub ahead of print. Go to original source... Go to PubMed...
  9. Casale M, Imbalzano E, Morabito C, et al. Early antithrombotic therapy and COVID-19: a better clinical course? New evidences from real-life cases. Cor Vasa 2020;62:37-40. Go to original source...
  10. Dattilo G, Falanga G, Casale M, et al. Oral Anticoagulants: Old and New Therapy. In: Bernhardt LV (Ed.). Advances in Medicine and Biology. New York: Nova Science Publishers, Inc., 2015:13-70.
  11. Dai WC, Zhang HW, Yu J, et al. CT Imaging and Differential Diagnosis of COVID-19. Can Assoc Radiol J 2020;71:195-200. Go to original source... Go to PubMed...
  12. Imbalzano E, Di Bella G, Lamari A, et al. Right ventricular myocardial deformation in young healthy subjects: A comparison study between 2D Strain and traditional parameters. Exp Clin Cardiol 2014;20:2729-2743.
  13. Dattilo G, Imbalzano E, Lamari A, et al. Ischemic heart disease and early diagnosis. Study on the predictive value of 2D strain. Int J Cardiol 2016;215:150-156. Go to original source... Go to PubMed...
  14. Ward RP, Lee L, Ward TJ, Lang RM. Utilization and appropriateness of trans-thoracic echocardiography in response to the COVID-19 pandemic. J AmSoc Echocardiogr 2020;33:691-692. Go to original source... Go to PubMed...
  15. Dattilo G, Lamari A, Di Bella G, et al. Treatment failure of low molecular weight heparin bridging therapy. Int J Cardiol 2013;167:e106-e107. Go to original source... Go to PubMed...
  16. Tulino D, Imbalzano E, Casale M, et al. Treatment failure of low molecular weight heparin in diabetic patient. Int J Cardiol 2013;168:e63-e64. Go to original source... Go to PubMed...
  17. Morabito C, Scarano M, Genovesi E, et al. Patent foramen ovale and paradoxical coronary artery embolism: rare event with great clinical relevance. Cor Vasa 2020;62:332-335. Go to original source...
  18. Casale M, Quattrocchi S, Bitto R, Dattilo G. Cardiac implantable devices and takotsubo syndrome. A rare but potential eventuality. Cor Vasa 2018;60:e500-e502. Go to original source...
  19. Casale M, Mezzetti M, Gigliotti De Fazio M, et al. Usefulness of Sacubitril/Valsartan in reduction of atrial fibrillation burden in a patient with ICD delivering inappropriate therapies. A new possibility? Cor Vasa 2020;62:336-339. Go to original source...
  20. Casale M, Mezzetti M, Tulino V, et al. Therapy of Cardiac Arrhythmias in Children: An Emerging Role of Electroanatomical Mapping Systems. Curr Vasc Pharmacol 2018;16:528-533. Go to original source... Go to PubMed...

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.





Cor et Vasa

You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.