Cor et Vasa, 2022 (vol. 64), issue 6

Original research articles

Evaluation of five algorithms in predicting the sublocalisation of right ventricular outflow tract arrhythmia (RVOTA) when compared to 3D electroanatomical mapping origin

Raluca Sirbu Prisecaru, Cristina Leatu, Leila Riahi, Victor Costache, Ioan Manitiu

Cor Vasa 2022, 64(6):571-578 | DOI: 10.33678/cor.2022.017

Aim: To compare the predictive accuracy of five different algorithms as verified by successful ablation site using 3D electroanatomical non-contact mapping in patients with symptomatic and asymptomatic but high ventricular burden right ventricular outflow tract (RVOT) tachycardias. Methods: 28 consecutive patients admitted for radiofrequency catheter ablation for symptomatic and asymptomatic, but high ventricular burden idiopathic premature ventricular contractions (PVC) were recruited for this study. All patients had previous failed or intolerant to beta-blocker and/or at least one class IC anti-arrhythmic agents, and they had normal left ventricular...

(Outcomes of personalised external aortic root support implantation in 100 patients in the Czech Republic)

Petr Němec, Jan Pirk, Ivo Skalský, Tomáš Matějka, Pavel Žáček, Tomáš Grus, Vilém Rohn, Petr Šantavý, Alice Krebsová, Ondrej Szárszoi, Lydie Tauchenová, Daniela Žáková, Radka Kočková, Petr Fila

Cor Vasa 2022, 64(6):579-583 | DOI: 10.33678/cor.2022.045

Dilatation of the aortic root and/or ascending aorta is associated with an increased risk of acute dissection. Personalized external aortic root support (PEARS) is a new method that was introduced in last years for these patients without any significant valve disease who do not fulfil the criteria for aortic root or ascending aorta replacement. It is a custom-made macroporous mesh that stabilises the aortic wall. We present the results of the first 100 consecutive patients in whom PEARS was implanted.

(Multicentric Observational prospective cohort STudy of the Heart Failure outpatients management in the Czech Republic - MOST-HF. Rationale and Design)

Filip Málek, Miloš Táborský, Ivan Málek, Tomáš Paleček, Lenka Špinarová, Jiří Vítovec, Jindřich Špinar, Vojtěch Melenovský, Jan Krejčí, Aleš Linhart, Radek Pudil, Petr Ošťádal, Jiří Veselý, Jana Kubátová, Jana Unar Vinklerová

Cor Vasa 2022, 64(6):585-587 | DOI: 10.33678/cor.2022.118

The prevalence of chronic heart failure syndrome is estimated to almost three percent of the total population in the Czech Republic and the number of patients still increases. The aim of the observational study is to map the current status of the medical and non-pharmacological therapy and the level of chronic heart failure outpatient care.

Association between reversine dose and increased plasticity of dedifferentiated fat (DFAT cells) into cardiac derived cells

Muhammad Firdani Ramadhan, Yudi Her Oktaviono, Budi Baktijasa Dharmadjati, Ryan Enast Intan

Cor Vasa 2022, 64(6):589-594 | DOI: 10.33678/cor.2022.033

Aim: To analyze the association between reversine and increased plasticity of DFAT into cardiac derivative cells. Method: The cultured DFAT cells were divided into four groups based on reversine dose: control (no reversine), 10 nM, 20 nM, and 40 nM reversine. Each group will go through several stages of passage before further differentiation into cardiomyocytes (marked by cTnT expression), VSCMs (marked by alpha-SMA expression), and vascular endothelial cells (marked by alpha-SMA expression) (marked by CD31 expression). Result: There were significant differences in the expression of cTnT, alpha-SMA, and CD31 (p = 0.003, p <0.001, and...

(Pulmonary embolism in Tábor Hospital: analysis of cohort and prevalence of pulmonary hypertension in long-term follow-up)

Jan Kuchař, Rostislav Král, Pavel Jansa

Cor Vasa 2022, 64(6):595-599 | DOI: 10.33678/cor.2022.027

Aim: The aim was to analyse the cohort of pulmonary embolism patients treated at Tábor hospital in the years 2016-2018 and to assess the prevalence and aetiology of persisting pulmonary hypertension in long-term follow-up. Methods: The cohort of pulmonary embolism cases was analysed retrospectively. Subsequent echocardiographic examinations, performed in Tábor Hospital, were identified. Probability of pulmonary hypertension was estimated according to the ESC guidelines. The aetiology of pulmonary hypertension was evaluated retrospectively based on echocardiographic and clinical parameters found in available documentation. Results: Total 283 cases of...

Pharmaco-Mechanical Thrombectomy vs. Conventional Anticoagulant Management of Acute Lower Extremity Deep Vein Thrombosis - Long-Term Outcomes

Orhan Rodoplu, Ibrahim Erdinc, Cuneyd Ozturk

Cor Vasa 2022, 64(6):601-610 | DOI: 10.33678/cor.2022.088

Objective: In this study, we aimed to evaluate the long-term effects of pharmaco-mechanical thrombectomy and compare its efficiency and safety against anticoagulation together with the use of compression stockings in patients with proximal deep vein thrombosis of the lower extremity. Methods: A total of 228 patients, between January 2013 and January 2020, who presented to the clinic with acute deep vein thrombosis of the lower extremity were investigated retrospectively. There were 112 pa- tients in the anticoagulation following pharmacomechanical thrombectomy group (Group 1) and 116 patients in the conventional anticoagulation with compression stockings...

Rashomon Effect on the Decision Process of Severe Coronary Artery Pathology: "Coronary Artery Bypass Surgery or Percutaneous Coronary Angioplasty"

Indelen Cenk, Kirali Mehmet Kaan

Cor Vasa 2022, 64(6):611-618 | DOI: 10.33678/cor.2022.077

Introduction: "Rashomon" is Kurosawa's masterpiece. Witnesses describe the same murder from different perspectives. But there is a difference between what they see and what they perceive. This is called the "Rashomon Effect". The aim of this study is to determine whether the mood of clinicians in different work environments has an effect on treatment indication decisions. Material and methods: The sample consisted of 54 clinicians, consisting of cardiologists (n = 29) and cardiovascular surgeons (n = 25). The angiography of a patient with severe coronary artery pathology was

Review articles

The journey of a patient with ACTA2 mutation - literature review and case report

Ivo Petrov, Assen Keltchev, Zoran Stankov, Strahil Vasilev

Cor Vasa 2022, 64(6):619-621 | DOI: 10.33678/cor.2022.023

Aortic pathologies are a main part of the cardiovascular disease specter. ACTA2 mutation is the main cause of familial thoracic aortic aneurysms and dissection, which is presented by dilation or dissection of the thoracic aorta in people, who do not have systemic or syndromic connective tissue disorder. The ACTA2 gene encodes the specific α-smooth muscle actin, which is an isoform of vascular smooth muscle actin. This mutation mainly leads to aortic pathologies, but it also presents a multisystemic smooth muscle dysfunction. We present a patient with typical clinical findings, consistent with an ACTA2 mutation and the treatment...

Cardiovascular autonomic control under obstructive sleep apnea combined with atrial fibrillation: Its role in pathogenesis and therapy

Mikhail V. Agaltsov, Nadezhda T. Obukhova, Anton R. Kiselev, Oxana M. Drapkina

Cor Vasa 2022, 64(6):622-627 | DOI: 10.33678/cor.2022.048

This review examines in detail the mechanisms of cardiovascular autonomic control in the course of sleep, during single and multiple repetitive episodes of apnea, their role in pathogenesis of atrial fibrillation (AF), and also highlights the methods of autonomic modulation. In conditions of a single or chronic exposure to obstructive sleep apnea, cardiovascular autonomic dysfunction is one of the leading factors providing the possibility of AF development and recurrence. A combined effect on AF risk factors (their modification, use of continuous positive airway pressure therapy, drug therapy, and interventional techniques) can normalize the autonomic...

(Modern ideas about the mechanisms of cardiac troponin release and their diagnostic role)

Aleksey M. Chaulin, Dmitry V. Duplyakov

Cor Vasa 2022, 64(6):628-636 | DOI: 10.33678/cor.2022.044

The main mechanism of cardiac troponin release (cTnT and cTnI) proven to date is ischemic necrosis of myocardial cells, which leads to the release of all intracellular molecules, including cTnT and cTnI into the bloodstream in acute myocardial infarction (AMI). However, in real clinical practice, doctors very often encounter many other (besides AMI) pathological conditions in which cTnT and cTnI concentrations in the bloodstream are elevated, but signs of myocardial ischemia are not observed. This clearly indicates the existence of other (non-ischemic) mechanisms of cardiomyocyte damage and the release of cTnT and cTnI into the bloodstream. Understanding...

Drug-induced pericarditis

Štefan Alušík, Zoltán Paluch

Cor Vasa 2022, 64(6):637-643 | DOI: 10.33678/cor.2022.047

Though not common, drug-induced pericarditis is a serious condition, since pericardial tamponade, should it develop, may be life-threatening. As the number of drugs is constantly expanding, so does the proportion of those capable of causing pericarditis. The authors reviewed the relevant literature in the PubMed database and complemented it with information from the VigiBase database. In their article, the authors present current knowledge about the mechanisms of origin and level of risk of drug-induced pericarditis and discuss relevant information on individual drugs divided into 7 classes. Some medicines are associated with a high risk of developing...

(Wearables, telemedicine, and artificial intelligence in arrhythmias and heart failure: Proceedings of the European Society of Cardiology Cardiovascular Round Table. Translation of the document prepared by the Czech Society of Cardiology)

Miloš Táborský, Josef Kautzner, Marián Fedorco, Karol Čurila, Hanka Wünschová, Jan Pyszko, Miroslav Novák, Milan Kozák, Martin Válek, Rostislav Polášek, Patrik Keprt, Milena Kubíčková, Jiří Plášek, Vít Gloger, Alan Bulava, Vlastimil Vančura, Tomáš Skála, Petr Pařízek, Josef Daněk

Cor Vasa 2022, 64(6):645-556 | DOI: 10.33678/cor.2022.123

Digital technology is now an integral part of medicine. Tools for detecting, screening, diagnosis, and monitoring health-related parameters have improved patient care and enabled individuals to identify issues leading to better management of their own health. Wearable technologies have integrated sensors and can measure physical activity, heart rate and rhythm, and glucose and electrolytes. For individuals at risk, wear- ables or other devices may be useful for early detection of atrial fibrillation or sub-clinical states of cardiovascular disease, disease management of cardiovascular diseases such as hypertension and heart failure, and lifestyle modification....

Case reports

Surgical Appearance of Aortic Involvement in Erdheim-Chester Disease: A Report of Two Cases

Umit Arslan, Ferhat Borulu, Oktay Tüydeş, Sevilay Ozmen, Bilgehan Erkut

Cor Vasa 2022, 64(6):657-660 | DOI: 10.33678/cor.2022.016

Erdheim-Chester disease (ECD), known as histiocytic neoplastic disease, can be diagnosed as a peripheral arterial disease because of its effects on vascular structures. Aortic involvement in ECD is usually recognised radiologically. However, there is insufficient information about the surgical appearance and treatment of aortic involvement in ECD. In this report, we presented a patient with ascending aortic involvement detected incidentally during coronary bypass and a patient with abdominal aortic involvement mimicking aortoiliac disease.

(A rare cause of heart failure)

Zuzana Komorová, Jan Krejčí, Eva Ozábalová, Roman Panovský, Věra Feitová, Michaela Rýznarová, Michal Hendrych, Ladislav Groch, Lenka Špinarová

Cor Vasa 2022, 64(6):661-664 | DOI: 10.33678/cor.2022.010

Infiltration of the heart in generalized lymphoma can lead to impaired cardiac function. Usually this manifests as heart failure, arrhythmias or systemic embolism. The case report describes a 64-year-old woman who presented with progressive shortness of breath and lower extremities edema. Extensive diagnostic workup including cardiac magnetic resonance imaging and CT scan revealed a well-defined, right-sided cardiac mass and generalized lymphadenopathy. The dimensions of the lesion were 90 × 80-90 × 90 mm and the tumor expanded predominantly into the right atrial septum and the mouth of the upper vena cava. In addition, the outflow tracts of both chambers...

(Conservative treatment of chronic disseminated intravascular coagulation caused by chronic dissection and aneurysm of thoracoabdominal aorta with rivaroxaban)

Monika Fialová, Jiří Nový, Jakub Šimka, Magdalena Oravcová, Radovan Malý, Jiří Cyrany

Cor Vasa 2022, 64(6):665-669 | DOI: 10.33678/cor.2022.013

Chronic disseminated intravascular coagulation (DIC) represents a life-threatening condition, in which activation of coagulation and fibrinolytic system occurs simultaneously, usually as a consequence of persistent weak or chronic intermittent activation of coagulation system. Especially in the population of elderly patients the possibility of aortic aneurysm and chronic aortic dissection as a precipitating factor needs to be considered. We present a case of 76-year-old woman with a history of thoracic endovascular aortic repair for aortic dissection Stanford type B four years earlier with repeated serious epistaxis during months, who was diagnosed...

(A rare complication of Tako-tsubo cardiomyopathy)

Martin Nerad, Dita Schaffelhoferová, Jiří Haniš

Cor Vasa 2022, 64(6):670-676 | DOI: 10.33678/cor.2022.036

Tako-tsubo cardiomyopathy, or stress cardiomyopathy, is a relatively rare and in most cases a reversible disease of the myocardium, with early signs being similar to an acute coronary syndrome. The pathophysiology isn't known to this day, the most accepted theory being an excess of catecholamines that probably plays a key role in stunning the myocardium. Excretion of catecholamines is mostly preceded by physical or emotional stress. In the first case report, we present a typical patient, in which Tako-tsubo syndrome was caused by long-lasting stress at work, being firstly misdiagnosed as a myocardial infarction. After making the diagnosis and proper...

Successful Repair of Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery (ALCAPA) using Pericardial Roll Graft: Case Report with Long-Term Follow-up

Dicky Fakhri, Putu Wisnu Arya Wardana, Abdurrahman Hadi, Pribadi W. Busro, Poppy S. Roebiono, Eva M. Marwali

Cor Vasa 2022, 64(6):677-679 | DOI: 10.33678/cor.2022.084

Background: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital heart defect that has serious challenges from diagnostic, surgical, to postoperative management. Case description: We report a 16-month-old patient, who underwent ALCAPA repair in our center. This patient came to the hospital with severe heart failure symptoms such as shortness of breath, cough and failure to thrive. Decreased left ventricle function and severe mitral valve regurgitation due to left ventricle dilatation was found. In this case, the left main artery (LMA) was not found and there were two ostial of the left anterior descending...

Images in cardiology

Acute occlusion of an anomalous left circumflex artery after aortic valve replacement

Branislav Bezák, Panagiotis Artemiou, Vladan Hudec, Ivo Gašparovič, Michal Hulman

Cor Vasa 2022, 64(6):681 | DOI: 10.33678/cor.2022.009

Reports

Zpráva z kongresu European Society for Vascular Surgery 2022 v Římě

MUDr. Kateřina Lawrie

Cor Vasa 2022, 64(6):691