Cor Vasa 2022, 64(6):661-664 | DOI: 10.33678/cor.2022.010
(A rare cause of heart failure)
- a Interní kardioangiologická klinika, Lékařská fakulta Masarykovy univerzity a Fakultní nemocnice u sv. Anny v Brně, Brno
- b Klinika zobrazovacích metod, Fakultní nemocnice u sv. Anny v Brně, Brno
- c I. patologicko-anatomický ústav, Lékařská fakulta Masarykovy univerzity a Fakultní nemocnice u sv. Anny v Brně, Brno
- d Mezinárodní centrum klinického výzkumu, Fakultní nemocnice u sv. Anny v Brně, Brno
Infiltration of the heart in generalized lymphoma can lead to impaired cardiac function. Usually this manifests as heart failure, arrhythmias or systemic embolism. The case report describes a 64-year-old woman who presented with progressive shortness of breath and lower extremities edema. Extensive diagnostic workup including cardiac magnetic resonance imaging and CT scan revealed a well-defined, right-sided cardiac mass and generalized lymphadenopathy. The dimensions of the lesion were 90 × 80-90 × 90 mm and the tumor expanded predominantly into the right atrial septum and the mouth of the upper vena cava. In addition, the outflow tracts of both chambers were also affected. Despite prompt and rigorous treatment, the patient died four days following admission due to sudden cardiac arrest. Post-mortem histological assessment verified a non-Hodgkin's diffuse B-cell lymphoma.
Keywords: Cardiac tumors, Heart failure, Lymphoma
Received: February 10, 2022; Revised: February 10, 2022; Accepted: February 17, 2022; Published: December 15, 2022 Show citation
References
- Zipes DP, Libby P, Bonow RO, et al., eds. Braunwald's heart disease: a textbook of cardiovascular medicine, Eleventh, international edition. Philadelphia, PA: Elsevier, 2019:233.
- McGee KP, Williamson EE, Martinez MW, Mayo Clinic, eds. Cardiac masses. In: Mayo Clinic guide to cardiac magnetic resonance imaging, Second edition, Mayo Clinic Scientific Press; Oxford University Press: Rochester, MN; Oxford; New York, 2015:163.
Go to original source...
- Kwong RY, Libby P. Cardiac and Pericardial Tumors. Cardiovascular Magnetic Resonance Imaging. Totowa, New Jersey, 2008:429-430, 447, 450.
Go to original source...
- Madron A, Dvořáček J, Paleček T. Primární lymfom srdce: od diagnostiky přes léčbu až k fatálním komplikacím. Cor Vasa 2019;61:e91-e95.
- Stouffer GA, Runge MS, Patterson C, et al., eds., Cardiac Tumors and Cardio-Oncology, in: Netter's cardiology, 3rd edition, Philadelphia, PA: Elsevier, 2019:486-488.
- Zamorano JL, Bax JJ, Rademakers FE, et al. Cardiac masses and tumors, in: ESC Textbook of Cardiovascular Imaging, Dordrecht: Springer, 2010:538, 547.
Go to original source...
- Bogaert J, Dymarowski S, Taylor AM, Muthurangu V. Cardiac masses, in: Clinical Cardiac MRI, 2nd ed., Heidelberg: Springer, 2012:411-412, 415-418.
Go to original source...
- Maleszewski JJ, Bois MC, Bois JP, et al. Neoplasia and the Heart: Pathological Review of Effects With Clinical and Radiological Correlation, J Am Coll Cardiol 2018;72:202-227.
Go to original source...
Go to PubMed...
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