Coronary ostial assessment of myeloperoxidase level correlated to severity of coronary artery disease

Noha Hassanin Hanboly, Yasser Kamel Gaber Baghdady, Mohammed Helmy Aly Ahmed, Assem Abdelaziz Hashad

Cor Vasa 2021, 63(6):646-650 | DOI: 10.33678/cor.2021.022  

Background: Myeloperoxidase participates in proatherogenic biological activities related to the evolution of cardiovascular disease including initiation, propagation, and acute complications of atherosclerotic process. Aim of study: We aimed to identify the relationship between myeloperoxidase (MPO) level at the ostium of coronary arteries and severity of coronary artery disease (CAD) . Methods: Our study population was divided into two groups: group A and B. Group A included 43 patients with non-ST elevation myocardial infarction (NSTEMI) who underwent coronary angiography. Group B included 43 subjects free from CAD as proved by stress ECG or stress...

Prognostic value of the combination of TIMI risk score and mean platelet volume to lymphocyte count ratio in patients with acute coronary syndrome

Emre Yilmaz, Ercan Aydin

Cor Vasa 2021, 63(6):652-660 | DOI: 10.33678/cor.2021.095  

Background: Thrombolysis In Myocardial Infarction (TIMI) risk score and MPV/lymphocyte ratio (MPVLR) are important parameters that can be used to predict mortality and major cardiovascular adverse events (MACE) in patients with acute coronary syndrome (ACS). However, the prognostic value of a modified score system that is based on the relationships and combinations of these parameters in ACS patients is unknown. Hence, we aimed to investigate the relationship between the modified risk score obtained by the combination of TIMI risk score and MPVLR with 2-year-long MACE and mortality in ACS patients., Method: In this study, 472 consecutive patients with...

Comparison of left ventricular deformity and twist parameters during Speckle Tracking with Philips iE33 and Affiniti 70 scanners

Denis Anatolyevich Shvets, Sergey Vladimirovich Povetkin

Cor Vasa 2021, 63(6):661-667 | DOI: 10.33678/cor.2021.104  

Aim: The purpose of this study was to compare the strain and twist parameters measured by Philips scanners with different software using the Speckle Tracking Echocardiography (STE) method. Material and methods of the study: 36 patients with the acute coronary syndrome (ACS) (unstable angina pectoris and myocardial infarction) were investigated on the ultrasonic scanners Philips iE33 (Q-lab, version 7.1, 2009) and Affiniti 70 (aCMQ, 2019) under the same conditions with an interval of 30 min. Scanning and measurement of the primary parameters were performed from the same apical and short-axis sections of the left ventricle (LV). Longitudinal strain (LS),...

Prognostic implication of uncontrolled hypertension in hospitalized patients with COVID-19

İbrahim Halil Özdemir, Bülent Özlek, Mehmet Burak Özen, Ramazan Gündüz, Nurullah Çetin

Cor Vasa 2021, 63(6):668-673 | DOI: 10.33678/cor.2021.062  

Objective: In this study, we aimed to investigate the effect of hypertension (HT) and antihypertensive treatment on prognosis, which is one of the cardiovascular risk factors affecting the prognosis of COVID-19. Methods: We included 117 patients diagnosed with COVID-19 by nasopharyngeal polymerase chain reaction (PCR). The patients were divided into a hypertensive group and a control group. Biochemical, complete blood count and imaging data of the patients were recorded. Mortality of patients with and without HT was evaluated. The effect of antihypertensive therapy on mortality was evaluated. Results: In thorax CT, ground glass opacity and pneumonic...

(Acute pulmonary embolism)

Margita Belicová, Dana Prídavková, Veronika Jankovičová, Miloslav Krajčík, Marian Mokáň

Cor Vasa 2021, 63(6):675-682 | DOI: 10.33678/cor.2021.109  

Background: Pulmonary embolism is relatively a frequent and dangerous disease with varied manifestations ranging from benign to fatal. The authors in a retrospective study presented a change in the incidence, diagnosis, and treatment of pulmonary embolism during the last 25 years. Methods: The authors performed a retrospective analysis of 860 (432 men) patients with definitely confirmed pulmonary embolism, who were hospitalized at the Department of Internal Medicine of University Hospital in Martin from January 1996 to December 2020. The source of information about patients were their medical documentations. The authors pointed view on an incidence,...

Systemic analysis of diagnostic performance and agreement between fractional flow reserve and quantitative flow ratio

Mindaugas Barauskas

Cor Vasa 2021, 63(6):683-687 | DOI: 10.33678/cor.2021.060  

Introduction: Physiology guided percutaneous coronary interventions (PCIs) are supported by experts worldwide. Despite its reliability, fractional flow reserve (FFR) method remains rarely used in clinical practice due to its cost and time-duration. The demand of physiology guided PCIs encouraged the search of faster, cheaper and not less reliable alternative coronary flow evalua- tion method. Since a novel minimally invasive FFR computation method has been presented interventional the of method FFR - and a novel alternative - quantitative flow ratio (QFR) - method has become a subject for numerous studies. Methods: In total, 23 publication representing...

Predictive value of Selvester QRS score for severity of coronary artery disease in ST-segment elevation myocardial infarction

Caner Türkoğlu, Ömer Genç, Taner Şeker, İbrahin Halil Kurt

Cor Vasa 2021, 63(6):689-696 | DOI: 10.33678/cor.2021.091  

Background: QRS score was demonstrated to be a strong predictor of infarct size and poor outcomes in patients with acute ST-segment elevation myocardial infarction (STEMI). Aim: We aimed to determine the association between the SYNTAX score II (SS-II) and QRS score in patients with STEMI. Methods: The study included 302 consecutive patients (71.8 % males, mean age 55.1±12.2 years) with STEMI who were treated with primary percutenous coronary intervention (PCI). The patients were divided into two groups according to their SS-II (SS-II ≤32 as low group [n = 241] and SS-II >32 as moderate-high group [n = 61]). Results: In-patients with moderate-high...

Association of anatomical defects of the inferior vena cava and gonadal veins with pelvic varicose veins

Anastasia A. Akulova, Abubakari I. Sidiki, Alexandr G. Faibushevich, Zaurbek Kh. Shugushev, Daniil A. Maximkin, Nikolay A. Talov, Olga V. Taranenko, Galina I. Veretnic

Cor Vasa 2021, 63(6):697-701 | DOI: 10.33678/cor.2021.068  

Knowledge of the clinical and anatomical variations of the pelvic venous system plays a significant role in the diagnosis and transcatheter methods of treatment of pelvic varicose veins. The most important characteristics of gonadal veins are identified by phlebography of the inferior vena cava and pelvic veins. These characteristics should be taken into account during endovascular interventions in order to avoid possible complications.

(Overview and application of validated algorithms using high-sensitivity cardiac troponin assays for early diagnosis of acute myocardial infarction)

Vladimír Jakubo, Tomáš Ondrúš, Miroslava Beňovská, Martin Doleček, Andrea Křivanová, Hana Šimáčková, Tomáš Zatočil, Petr Kala, Jiří Pařenica, Petr Lokaj

Cor Vasa 2021, 63(6):703-709 | DOI: 10.33678/cor.2021.064  

Chest pain is one of the leading reasons for emergency department visits and the chief symptom of acute myocardial infarction (AMI). The measurement of myocardial injury biochemical markers' blood level is essential for the diagnosis of AMI. Cardiac troponin is the current international gold standard marker. The contemporary expansion in the usage of high-sensitivity assays that can detect cardiac troponin at very low levels presents a challenge for accurate interpretation of results. European Society of Cardiology guidelines prioritize the employment of validated rule out/rule in algorithms to rule out AMI safely and rapidly and/or to early identification...

Left main bronchus compression by aneurysm and kinking of the descending aorta

Andrey Slautin, Vladimír Mikulenka, Jaroslav Hlubocký, Jaroslav Lindner

Cor Vasa 2021, 63(6):710-713 | DOI: 10.33678/cor.2021.024  

Představujeme kazuistiku 71leté pacientky s kompresí levého hlavního bronchu aneurysmatem descendentní aorty, která se projevila progresivní dušností, kašlem a hemoptýzou bez přítomnosti teploty. Osobní anamnéza pacientky zahrnuje opakované respirační infekce, chronický kašel, hospitalizaci pro levostrannou pneumonii. Během CT vyšetření bylo zjištěno aneurysma ascendentní aorty, dilatace a kinking descendentní aorty s útlakem levého hlavního bronchu. Zavedení stentu do bronchiálního lumen nemělo úspěch, proto byl u pacientky indikován chirurgický výkon, kdy byla provedena náhrada descendentní aorty. Útlak hlavního bronchu aneurysmatem a kinkingem aorty...

Chronic heart failure and hypotensive effects of sacubitril/valsartan. A clinical case

Claudia Morabito, Marianna Gigliotti De Fazio, Francesca Parisi, Elisabetta Demurtas, Luana Orlando, Michele Scarano

Cor Vasa 2021, 63(6):715-718 | DOI: 10.33678/cor.2021.069  

Background: Heart failure (HF) with reduced ejection fraction (HFrEF) is a significant public health issue, affecting more than 2% of general population. Therapy includes multiple medications proven to decrease mortality and hospitalization rates. Despite strong guideline recommendations, dosing in routine clinical practice has traditionally failed to reach the same levels achieved in clinical trials. The same seems to occur with sacubitril/valsartan but the benefits are still satisfactory. Case presentation: We report the case of a 67-year-old male patient suffering from HFrEF resulting from dilated cardiomyopathy who started therapy with sacubitril/valsartan....

(Carcinoid heart disease in a patient with primary ovarian carcinoid)

Eva Kapsová, Jan Václavík, Tomáš Veiser, Patricie Delongová

Cor Vasa 2021, 63(6):720-724 | DOI: 10.33678/cor.2021.050  

Carcinoid heart disease is a collective term for all heart diseases that result from the action of neurohumoral substances produced by carcinoids. In most cases, it is a dysfunction of right-sided heart valves, predominantly the tricuspid valve’s insuffi ciency, leading to right heart failure. A small proportion of patients, up to approximately 10%, may also affect the mitral and aortic valves. In the case report, we present a patient diagnosed with a rare primary ovarian carcinoid, clinically present carcinoid syndrome, including both rightand left-sided heart valve involvement and rapid clinical progression of the disease.

Triple oral combination therapy in patients with idiopathic pulmonary arterial hypertension and recurrent vessel dissection of inoperable pulmonary artery aneurysm

Marco Vatrano, Luana Orlando, Francesco Cassadonte, Pierpaolo Di Micco, Vincenzo Antonio Ciconte, Vincenzo Russo, Egidio Imbalzano

Cor Vasa 2021, 63(6):726-731 | DOI: 10.33678/cor.2021.089  

Background: Pulmonary artery aneurysm is a rare condition related to the stress that the vascular wall undergoes with progressive dilation. A clear definition and its prevalence are not available. Pulmonary arterial hypertension is also a life-threatening and progressive condition which requires specific therapies. Case report: We describe the case of a 62-year-old Caucasian woman with idiopathic pulmonary arterial hypertension and inoperable giant pulmonary artery aneurysm associated with recurrent vessel dissection. Diagnosis was simple with the use of echocardiography and computed tomography. Conversely, deciding on the treatment was difficult,...

The importance of differentiating types of myxoma: a case report

Tri W. Soetisna, Lisca Namretta, Edward S. Tirta, M. Marliando S. P. Catur, Bagus Ronidipta, Amin Tjubandi

Cor Vasa 2021, 63(6):733-735 | DOI: 10.33678/cor.2021.063  

Myxoma shows unspecific symptoms similar to other cardiac disorders. Late resection of myxoma will worsen output such as congestive heart failure, cardiac arrhythmia, and cardiac embolism, causing sudden death. Early diagnosis and surgical excision of cardiac myxomas, especially with the villous surface, must be done as soon as possible. Additional diagnostic examination was needed to define types of myxoma for earlier treatment to prevent complications. We present a case of atrial myxoma which was diagnosed and treated earlier than the median time reviewed by the previous study. This paper focuses on the importance of early diagnosis and defining...

(Ferric carboxymaltose - a promising molecule in the treatment of iron deficiency in patients with heart failure)

Mária Bakošová, Jan Krejčí, Lenka Špinarová

Cor Vasa 2021, 63(6):737-740 | DOI: 10.33678/cor.2021.137  

The authors summarize the new findings on iron deficiency in patients with heart failure recently reflected in the new guidelines for the management of the heart failure. In addition to recapitulating previous evidence, they discuss the results of the AFFIRM-HF trial, which extended the indication of ferric carboxymaltose to patients after acute decompensation of heart failure. It has been shown that after intravenous iron supplementation there is an improvement in symptoms, performance and a reduction in hospital admissions for heart failure decompensation. The text is supplemented by a case report describing the case of a 60-year-old female patient...

Dilated right cardiac chamber delusion solved by cardiovascular magnetic resonance

Catarina Costa, Ricardo Pinto, Teresa Pinho, André Carvalho, Cristina Cruz, António Madureira, Filipe Macedo

Cor Vasa 2021, 63(6):741-742 | DOI: 10.33678/cor.2021.031  

Extensive calcification of the interventricular septum with caseous cavity deriving from stenotic aortic valve

Branislav Bezák, Panagiotis Artemiou, Juraj Grebáč, Dávid Kocan, Michal Hulman

Cor Vasa 2021, 63(6):743 | DOI: 10.33678/cor.2021.065  

(Appropriate indications to cardiac computed tomography (CT): expert consensus statement of the Section of Cardiac Computed Tomography of the Czech Association of Cardiovascular Imaging Methods of the Czech Society of Cardiology)

Petr Kuchynka, Theodor Adla, Jan Baxa, David Zemánek, Milan Kamínek, Hana Línková, Radka Kočková

Cor Vasa 2021, 63(6):745-747 | DOI: 10.33678/cor.2021.122  

(Antithrombotic therapies in aortic and peripheral arterial diseases in 2021: a consensus document from the ESC working group on aorta and peripheral vascular diseases, the ESC working group on thrombosis, and the ESC working group on cardiovascular pharmacotherapy. Translation of the document prepared by the Czech Society of Cardiology and the Czech Society of Angiology of ČLS JEP)

Miloš Táborský, Aleš Linhart, Debora Karetová, Tomáš Skála, Zuzana Moťovská, Martin Köcher, Petr Štádler

Cor Vasa 2021, 63(6):748-759 | DOI: 10.33678/cor.2021.131  

The aim of this collaborative document is to provide an update for clinicians on best antithrombotic strategies in patients with aortic and/or peripheral arterial diseases. Antithrombotic therapy is a pillar of optimal medical treat- ment for these patients at very high cardiovascular risk. While the number of trials on antithrombotic therapies in patients with aortic or peripheral arterial diseases is substantially smaller than for those with coronary artery disease, recent evidence deserves to be incorporated into clinical practice. In the absence of specific indications for chronic oral anticoagulation due to concomitant cardiovascular disease,...

XIX. konference České asociace akutní kardiologie Hotel Thermal, Karlovy Vary, 5.–7. 12. 2021

redakce

Cor Vasa 2021, 63(6):764-771  

Jiří Vítovec, Jindřich Špinar, Lenka Špinarová, Ondřej Ludka a kolektiv: Léčba kardiovaskulárních onemocnění

Jan Petrášek

Cor Vasa 2021, 63(6):763  

Prof. MUDr. Pavel Gregor, DrSc., FESC – vzor poctivého lékaře a skvělého vědce

Petr Widimský, Michael Aschermann

Cor Vasa 2021, 63(6):761-762