Cor Vasa 2021, 63(6):689-696 | DOI: 10.33678/cor.2021.091
Predictive value of Selvester QRS score for severity of coronary artery disease in ST-segment elevation myocardial infarction
- a Department of Cardiology, Malatya Training and Research Hospital, Malatya, Turkey
- b Department of Cardiology, Ağri Training and Research Hospital, Ağri, Turkey
- c Department of Cardiology, Adana City Training and Research Hospital, Adana, Turkey
Background: QRS score was demonstrated to be a strong predictor of infarct size and poor outcomes in patients with acute ST-segment elevation myocardial infarction (STEMI).
Aim: We aimed to determine the association between the SYNTAX score II (SS-II) and QRS score in patients with STEMI.
Methods: The study included 302 consecutive patients (71.8 % males, mean age 55.1±12.2 years) with STEMI who were treated with primary percutenous coronary intervention (PCI). The patients were divided into two groups according to their SS-II (SS-II ≤32 as low group [n = 241] and SS-II >32 as moderate-high group [n = 61]).
Results: In-patients with moderate-high SS-II score were older. Level of N-terminal pro-B-type natriuretic peptide (NT-proBNP), troponin, wall motion score index and TIMI frame count were significantly higher in the moderate-high SS-II group than in the low SS-II group (p <0.05, for all). Patients with moderate-high SS-II had low ejection fraction (p <0.001). The composite outcome that consists of in-hospital all-cause mortality and major cardiovascular adverse events was significantly higher in the moderate-high SS-II group (p = 0.01). Selvester QRS score was significantly higher in moderate-high SS-II group than in the low SS-II group (p <0.001). QRS score, hypertension, smoking and TIMI frame count were found to be independent predictors of the moderate-high SS-II. The cut-off value of QRS score for predicting SS-II on the basis of receiver operating characteristic (ROC) curve analysis was 9.0, with 50.9% sensitivity and 84.1% specificity (AUC: 0.726, 95% CI: 0.648-0.804, p <0.001).
Conclusion: QRS score is associated with SS-II predicting the severity of coronary artery disease and mortality in patients with STEMI undergoing primary PCI.
Keywords: Hypertension, Selvester QRS score, ST-segment elevation myocardial infarction, SYNTAX score-II, TIMI frame count
Received: June 13, 2021; Revised: June 13, 2021; Accepted: July 26, 2021; Published: December 13, 2021 Show citation
ACS | AIP | APA | ASA | Harvard | Chicago | Chicago Notes | IEEE | ISO690 | MLA | NLM | Turabian | Vancouver |
References
- Reindl M, Reinstadler SJ, Feistritzer HJ, et al. Persistent T-wave inversion predicts myocardial damage after ST-elevation myocardial infarction. Int J Cardiol 2017;241:76-82.
Go to original source...
Go to PubMed...
- Selvester RH, Wagner GS, Hindman NB. The Selvester QRS scoring system for estimating myocardial infarct size. The development and application of the system. Arch Intern Med 1985;145:1877-1881.
Go to original source...
- Bounous EP Jr, Califf RM, Harrell FE Jr, et al. Prognostic value of the simplified Selvester QRS score in patients with coronary artery disease. J Am Coll Cardiol 1988;11:35-41.
Go to original source...
Go to PubMed...
- Palmeri ST, Harrison DG, Cobb FR, et al. QRS Scoring System for Assessing Left Ventricular Function After Myocardial Infarction. N Engl J Med 1982;306:4-9.
Go to original source...
Go to PubMed...
- Sianos G, Morel MA, Kappetein AP, et al. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention 2005;1:219-227.
Go to PubMed...
- Farooq V, van Klaveren D, Steyerberg EW, et al. Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II. Lancet 2013;381:639-650.
Go to original source...
Go to PubMed...
- Campos CM, van Klaveren D, Iqbal J, et al. Predictive performance of SYNTAX score II in patients with left main and multivessel coronary artery disease. Circ J 2014;78:1942-1949.
Go to original source...
Go to PubMed...
- Magro M, Nauta S, Simsek C, et al. Value of the SYNTAX score in patients treated by primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: The MI SYNTAX score study. Am Heart J 2011;161:771-781.
Go to original source...
Go to PubMed...
- Wang G, Wang C, Zhang Y, et al. Usefulness of the SYNTAX score II to predict 1-year outcome in patients with primary percutaneous coronary intervention. Coron Artery Dis 2016;27:483-489.
Go to original source...
Go to PubMed...
- Tricoci P, Leonardi S, White J, et al. Cardiac troponin after percutaneous coronary intervention and 1-year mortality in non-ST-segment elevation acute coronary syndrome using systematic evaluation of biomarker trends. J Am Coll Cardiol 2013;62:242-251.
Go to original source...
Go to PubMed...
- Palmerini T, Genereux P, Caixeta A, et al. Prognostic value of the SYNTAX score in patients with acute coronary syndromes undergoing percutaneous coronary intervention: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) trial. J Am Coll Cardiol 2011;57:2389-2397.
Go to original source...
- Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J 2018;72:2231-2264.
Go to original source...
Go to PubMed...
- Cockcroft DW, Gault H. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
Go to original source...
Go to PubMed...
- Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr 1989;2:358-367.
Go to original source...
Go to PubMed...
- Karabağ Y, Çağdaş M, Rencuzogullari I, et al. Comparison of SYNTAX score II efficacy with SYNTAX score and TIMI risk score for predicting in-hospital and long-term mortality in patients with ST segment elevation myocardial infarction. Int J Cardiovasc Imaging 2018;34:1165-1175.
Go to PubMed...
- Ideker RE, Wagner GS, Ruth WK, et al. Selvester RH. Evaluation of a QRS scoring system for estimating myocardial infarct size. II. Correlation with quantitative anatomic findings for anterior infarcts. Am J Cardiol 1982;49:1604-1614.
Go to original source...
Go to PubMed...
- Shiomi H, Kosuge M, Morimoto T, et al. CREDO-Kyoto AMI Investigators. QRS score at presentation electrocardiogram is correlated with infarct size and mortality in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention. Circ J 2017;81:1129-1136.
Go to original source...
Go to PubMed...
- Uyarel H, Cam N, Okmen E, et al. Level of Selvester QRS score is predictive of ST-segment resolution and 30-day outcomes in patients with acute myocardial infarction undergoing primary coronary intervention. Am Heart J 2006;151:e1231-e1237.
Go to original source...
Go to PubMed...
- Tjandrawidjaja MC, Fu Y, Westerhout CM, et al. Usefulness of the QRS score as a strong prognostic marker in patients discharged after undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Am J Cardiol 2010;106:630-634.
Go to original source...
Go to PubMed...
- Petrie CJ, Weir RA, Anwar MS, et al. High sensitivity troponin T in acute medicine; more questions than answers. QJM 2014;107:193-200.
Go to original source...
Go to PubMed...
- Yamazaki K, Iijima R, Nakamura M, Sugi K. High-sensitivity cardiac troponin T level is associated with angiographic complexity of coronary artery disease: a cross-sectional study. Heart Vessels 2016;31:890-896.
Go to original source...
Go to PubMed...
- Eek C, Grenne B, Brunvand H, et al. Strain echocardiography and wall motion score index predicts final infarct size in patients with non-ST-segment-elevation myocardial infarction. Circ Cardiovasc Imaging 2010;3:187-194.
Go to original source...
Go to PubMed...
- Jurado-Roman A, Agudo-Quilez P, Rubio-Alonso B, et al. Superiority of wall motion score index over left ventricle ejection fraction in predicting cardiovascular events after an acute myocardial infarction. Eur Heart J Acute Cardiovasc Care 2019;8:78-85.
Go to original source...
Go to PubMed...
- Çağdaş M, Rencüzoğullari I, Karakoyun S, et al. Assessment of relationship between C-reactive protein to albumin ratio and coronary artery disease severity in patients with acute coronary syndrome. Angiology 2019;70:361-368.
Go to PubMed...
- Zhang C, Jiang L, Xu L, et al. Implications of N-terminal pro-B-type natriuretic peptide in patients with three-vessel disease. Eur Heart J 2019;40:3397-3405.
Go to original source...
Go to PubMed...
- Lee JH, Kim JH, Jang SY, et al. A new tool for the risk stratification of patients undergoing primary percutaneous coronary intervention with ST-segment elevation myocardial infarction: Bio-Clinical SYNTAX score. Int J Cardiol 2015;187:193-195.
Go to original source...
Go to PubMed...
- Barbash GI, White HD, Modan M, Van der Werf F. Smoking and acute myocardial infarction. Circulation 1993;87:1427-1428.
Go to original source...
Go to PubMed...
- Albertal M, Cura F, Escudero AG, et al. Mechanism involved in the paradoxical effects of active smoking following primary angioplasty: a subanalysis of the protection of distal embolization in high-risk patients with acute myocardial infarction trial. J Cardiovasc Med 2008;9:810-812.
Go to original source...
Go to PubMed...
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.