Cor Vasa 2023, 65(4):604-609 | DOI: 10.33678/cor.2022.110

The Usefulness of RDW as a Predictor of Atrial Fibrillation Recurrence after Cryoablation

Pinar Keskina, Halil Lutfi Kisacika, Sinan Incib, Murat Gulb, Ozcan Ozekea, Serkan Topaloglua, Dursun Arasa
a Departmant of Cardiology, Yuksek Ihtisas Education and Research Hospital, Ankara, Turkey
b Department of Cardiology, School of Medicine, Aksaray University, Aksaray, Turkey

Aim: Red cell distribution width (RDW) is known to be related to inflammation and has been associated with poor outcomes in patients with cardiovascular diseases. However, little is known about the role of RDW as a predictor of atrial fibrillation (AF) recurrence after cryoablation, and thus we aimed to investigate the relation between RDW and the recurrence of AF after cryoablation.

Methods: We retrospectively analyzed the case records of 90 patients after cryoablation (mean age, 50.06±12.36) with symptomatic paroxysmal AF despite being prescribed at least one anti-arrhythmic drug. The patients were divided into two groups based on the recurrence of AF and, after a mean follow-up period of 15 months.

Results: AF recurrence was detected in 22 (24%) patients. Baseline demographic characteristics and left atrial diameter (3.74±0.33 vs 3.76±0.31; p = 0.757) were similar between the two groups. RDW levels were significantly higher in patients with AF recurrence than in those without AF recurrence (14.17±1.42 vs 13.57±0.85; p = 0.019). CHA2DS2-VASc scores were not different between the two groups but in the patients with a CHA2DS2-VASc score of 3, the rate of AF recurrence was 46% while it was only 15% in patients with CHA2DS2-VASc score 0. The value of RDW as a predictor of a recurrence of AF was tested using the receiver operator characteristic curve and the area under the curve was 0.634 (p = 0.06) with a trend toward statistical significance.

Conclusion: RDW may be a useful predictor of AF recurrence along with other predictors but not alone, and larger multicenter and prospective studies are required to confirm this.

Keywords: Atrial fibrillation, Cryoablation, RDW

Received: August 30, 2022; Revised: September 30, 2022; Accepted: October 14, 2022; Published: September 1, 2023  Show citation

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Keskin P, Lutfi Kisacik H, Inci S, Gul M, Ozeke O, Topaloglu S, Aras D. The Usefulness of RDW as a Predictor of Atrial Fibrillation Recurrence after Cryoablation. Cor Vasa. 2023;65(4):604-609. doi: 10.33678/cor.2022.110.
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