Cor Vasa 2021, 63(1):73-78 | DOI: 10.33678/cor.2020.105

(Cardiac allograft vasculopathy nowadays)

Tomáš Eckhardt, Michal Pazderník
Klinika kardiologie, Institut klinické a experimentální medicíny, Praha

Cardiac allograft vasculopathy is the main cause of late morbidity and mortality in heart transplant patients and significantly shortens their long-term survival. It is characterized by a diffuse concentric intimal hyperplasia, which manifests itself in the form of early stenotic coronary artery disease. The diagnosis should be made on the basis of a combination of findings from non-invasive and invasive examinations. Treatment options are limited, hence prevention of its development is crucial. This article discusses the epidemiology, symptoms, pathogenesis, risk factors, diagnosis and treatment of this disease.

Keywords: Cardiac allograft vasculopathy, Intimal hyperplasia, Optical coherence tomography, Transplantation,

Received: November 10, 2020; Revised: November 10, 2020; Accepted: November 17, 2020; Published: February 25, 2021  Show citation

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Eckhardt T, Pazderník M. (Cardiac allograft vasculopathy nowadays). Cor Vasa. 2021;63(1):73-78. doi: 10.33678/cor.2020.105.
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