Cor Vasa 2026, 68(5):574-583 | DOI: 10.33678/cor.2026.067

(Innovations and new approaches in cardiac resynchronization therapy)

Jan Řeháček, Petr Oą»ádal, Jakub Honěk
Kardiologická klinika, 2. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Motol a Homolka, pracoviątě Motol, Praha, Česká republika

The article summarizes the key directions and innovations in cardiac resynchronization therapy with the greatest anticipated impact on clinical practice. The introduction discusses the pathophysiology of cardiac dyssynchrony and reviews diagnostic methods and workflows (including modern techniques such as ultra -high-frequency ECG and new approaches to ultrasound assessment). In subsequent sections, we also describe new techniques for lead implantation including His bundle pacing and left bundle branch area pacing. These approaches aim to reduce the proportion of patients who do not respond to resynchronization therapy.

Keywords: Cardiac dyssynchrony, Cardiac resynchronization therapy, Conduction system pacing, Heart failure, Left bundle branch area pacing

Received: January 9, 2026; Revised: January 9, 2026; Accepted: July 23, 2026; Prepublished online: September 23, 2026; Published: October 20, 2026  Show citation

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Řeháček J, Oą»ádal P, Honěk J. (Innovations and new approaches in cardiac resynchronization therapy). Cor Vasa. 2026;68(5):574-583. doi: 10.33678/cor.2026.067.
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