Cor Vasa 2025, 67(2):302-304 | DOI: 10.33678/cor.2024.085

Myocardial infarction in a young patient with antiphospholipid syndrome: A case report

Marta Catarina Bernardo, Catarina Ribeiro Carvalho, Catarina Ferreira, Inês Silveira, Ana Batista, Sofia Silva Carvalho, Ilídio Moreira
Cardiology Department, Unidade Local de Saúde de Trás-os-Montes e Alto Douro, Portugal

This case report highlights the importance of a multimodal approach, tailored therapeutic interven- tions, and the poor prognosis of myocardial infarction with non-obstructive coronary arteries (MINOCA) in a young patient with antiphospholipid syndrome (APS). A 39-year-old man was admitted with a diagnosis of a ST elevation myocardial infarction (STEMI), in Killip class III. Angiography showed absence of obstructive epicardial coronary artery disease prompting further evaluation with cardiac magnetic resonance imaging (MRI). It revealed infarction scars in multiple arterial territories and severe left ventricular dysfunction. The patient evolved with heart failure with reduced ejection fraction and a subcutaneous implantable cardioverter-defibrillator was implanted.

Keywords: Antiphospholipid syndrome, Myocardial infarction, Subcutaneous implantable cardioverter-defibrillator

Received: July 23, 2024; Revised: October 3, 2024; Accepted: October 14, 2024; Prepublished online: March 25, 2025; Published: May 1, 2025  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Catarina Bernardo M, Carvalho CR, Ferreira C, Silveira I, Batista A, Carvalho SS, Moreira I. Myocardial infarction in a young patient with antiphospholipid syndrome: A case report. Cor Vasa. 2025;67(2):302-304. doi: 10.33678/cor.2024.085.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Lóczi L, Kappelmayer J, Tarr T, Bagoly Z. Antiphospholipid syndrome and the risk of myocardial infarction: current evidence and uncertainties. Kardiol Pol 2020;78:6-14. Go to original source... Go to PubMed...
    2. Chezel J, Fischer Q, Nicaise Roland P, et al. Primary antiphospholipid syndrome revealed by acute myocardial infarction in young adults: a prospective observational study. Thromb Res 2021;198:151-153. Go to original source... Go to PubMed...
    3. Agewall S, Beltrame JF, Reynolds HR, et al. ESC working group position paper on myocardial infarction with non-obstructive coronary arteries. Eur Heart J 2017;38:143-153. Go to original source... Go to PubMed...
    4. Yildiz M, Ashokprabhu N, Shewale A, et al. Myocardial infarction with non-obstructive coronary arteries (MINOCA). Front Cardiovasc Med 2022;9:1032436. Go to original source... Go to PubMed...
    5. Pelliccia F, Pasceri V, Niccoli G, et al. Predictors of Mortality in Myocardial Infarction and Nonobstructed Coronary Arteries: A Systematic Review and Meta-Regression. Am J M 2020;133:73.e4-83.e4. Go to original source... Go to PubMed...
    6. Mileva N, Paolisso P, Gallinoro E, et al. Diagnostic and Prognostic Role of Cardiac Magnetic Resonance in MINOCA: Systematic Review and Meta-Analysis. JACC Cardiovasc Imaging 2023;16:376-389. Go to original source... Go to PubMed...
    7. Rallidis LS, Xenogiannis I, Brilakis ES, Bhatt DL. Causes, Angiographic Characteristics, and Management of Premature Myocardial Infarction: JACC State-of-the-Art Review. J Am Coll Cardiol 2022;79:2431-2449. Go to original source... Go to PubMed...
    8. Kolitz T, Shiber S, Sharabi I, et al. Cardiac Manifestations of Antiphospholipid Syndrome With Focus on Its Primary Form. Front Immunol 2019;10:941. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content


    Cor et Vasa

    You are accessing a site intended for medical professionals, not the lay public. The site may also contain information that is intended only for persons authorized to prescribe and dispense medicinal products for human use.

    I therefore confirm that I am a healthcare professional under Act 40/1995 Coll. as amended by later regulations and that I have read the definition of a healthcare professional.


    No
    Yes