Cor Vasa 2024, 66(6):623-627 | DOI: 10.33678/cor.2024.087

Exploring Post-Transfusion Pulmonary Edema: Differentiating Transfusion-Associated Circulatory Overload (TACO) from Transfusion-Related Acute Lung Injury (TRALI)

Meity Ardianaa, Annisa Trissatharraa, Inna Maya Sufiyaha, Bambang Herwantoa, Wynne Widiartib
a Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
b Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Transfusion-associated circulatory overload (TACO) and transfusion-related acute lung injury (TRALI) represent significant contributors to transfusion-related morbidity and mortality. This case study involves a 28-year-old female patient presenting with shortness of breath following a transfusion. The diagnostic approach relied on physical examination, chest x-ray, basic laboratory tests, and echocardiography. The challenges included difficulty in establishing the diagnosis between TACO, TRALI, or a combination thereof due to limited awareness, poorly defined diagnostic criteria, and the lack of specific therapeutic interventions. These complexities underscore the need for enhanced recognition and management strategies for these transfusion-associated complications.

Keywords: Lung edema, TACO, TRALI, Transfusion

Received: May 5, 2024; Revised: September 28, 2024; Accepted: October 15, 2024; Prepublished online: June 2, 2012; Published: December 20, 2024  Show citation

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Ardiana M, Trissatharra A, Sufiyah IM, Herwanto B, Widiarti W. Exploring Post-Transfusion Pulmonary Edema: Differentiating Transfusion-Associated Circulatory Overload (TACO) from Transfusion-Related Acute Lung Injury (TRALI). Cor Vasa. 2024;66(6):623-627. doi: 10.33678/cor.2024.087.
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