Cor Vasa 2024, 66(3):370-374 | DOI: 10.33678/cor.2024.009
Venous Thromboembolism, an Unusual Complication of Infective Endocarditis Caused by Moraxella species: a Case Report
- a Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Hospital, Surabaya, Indonesia
- b Medical Faculty of Airlangga University - Dr. Soetomo General Hospital, Surabaya, Indonesia
Background: Septic embolism is a relatively common and potentially severe complication of infective endocarditis (IE), and most often are found in the brain, solid organs (e.g. spleen, kidney, lungs), and lower extremity. Interestingly, we found an acute venous thromboembolic event in IE patient with septicemia. Case illustration: A 42-year-old male was referred from neighboring island to our hospital for IE and septic shock. On admission he complained of shortness of breath during heavy activity, with fatigue and fever for seven days. He also presented with acute onset of left upper extremity pain for three days. The pain was increased over time with burning sensation, exacerbated by activity, and there were no relieving factors. The left upper extremity looks bluish with bruising, accompanied by tenderness, and warm to touch. Laboratory examination showed leukocytosis (24.7 × 109/L), thrombocytopenia (65 × 109/L), elevated transaminase (SGOT 3.920 and SGPT 1.836), elevated serum creatinine (4.1 mg/dL), with an elevated infection marker (CRP 5.42 mg/L and procalcitonin 1.03 μg/L). Echocardiography showed severe mitral regurgitation (MR) with
Keywords: Infective endocarditis,, Moraxella species, Venous thromboembolism
Received: October 22, 2023; Revised: October 22, 2023; Accepted: February 2, 2024; Prepublished online: June 2, 2012; Published: June 28, 2024 Show citation
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References
- Chen H, Zhan Y, Zhang K, et al. The Global, Regional, and National Burden and Trends of Infective Endocarditis From 1990 to 2019: Results From the Global Burden of Disease Study 2019. Front Med (Lausanne) 2022;9:774224.
Go to original source...
Go to PubMed...
- Shah S, Clarke LG, Shields RK. Epidemiology and Clinical Outcomes of Non-HACEK Gram-Negative Infective Endocarditis. Open Forum Infect Dis 2023;10:ofad052.
Go to original source...
Go to PubMed...
- Cimmino G, Bottino R, Formisano T, et al. Current Views on Infective Endocarditis: Changing Epidemiology, Improving Diagnostic Tools and Centering the Patient for Up-to-Date Management. Life 2023;13:377.
Go to original source...
Go to PubMed...
- Liesenborghs L, Meyers S, Vanassche T, Verhamme P. Coagulation: At the heart of infective endocarditis. J Thromb Haemost 2020;18:995-1008.
Go to original source...
Go to PubMed...
- Galli E, Maggio E, Pomero F. Venous Thromboembolism in Sepsis: From Bench to Bedside. Biomedicine 2022;10:1651.
Go to original source...
Go to PubMed...
- Colling ME, Tourdot BE, Kanthi Y. Inflammation, Infection and Venous Thromboembolism. Circ Res 2021;128:2017-2036.
Go to original source...
Go to PubMed...
- Habib G, Lancellotti P, Antunes MJ, et al. 2015 ESC Guidelines for the management of infective endocarditis. Eur Heart J 2015;36:3075-3123.
Go to original source...
Go to PubMed...
- Falcone M, Tiseo G, Durante-Mangoni E, et al. Risk Factors and Outcomes of Endocarditis Due to Non-HACEK Gram-Negative Bacilli: Data from the Prospective Multicenter Italian Endocarditis Study Cohort. Antimicrob Agents Chemother 2018;62:e02208-e02217.
Go to original source...
Go to PubMed...
- Ioannou P, Alexakis K, Baliou S, Kofteridis DP. Infective Endocarditis by Moraxella Species: A Systematic Review. J Clin Med 2022;11:1854.
Go to original source...
Go to PubMed...
- Maierean SM, Marinescu DC, Croitoru DO, Verma AA. Infectious endocarditis and vertebral osteomyelitis caused by Moraxella catarrhalis. BMJ Case Rep 2019;12:e228776.
Go to original source...
Go to PubMed...
- Yellapu V, Ackerman D, Longo S, Stawicki SP. Septic Embolism in Endocarditis: Anatomic and Pathophysiologic Considerations. In: Advanced Concepts in Endocarditis. InTech 2018. doi: 10.5772/intechopen.76766.
Go to original source...
- Mayekar MV, Jadhav US, Ghewade B, et al. Septic Pulmonary Embolism With Deep Vein Thrombosis and Bilateral Pleural Effusion. Cureus 2022;14:e29437.
Go to original source...
Go to PubMed...
- Lichota A, Gwozdzinski K, Szewczyk EM. Microbial modulation of coagulation disorders in venous thromboembolism. J Inflamm Res 2020;13:387-400.
Go to original source...
Go to PubMed...
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