Cor Vasa 2022, 64(6):637-643 | DOI: 10.33678/cor.2022.047

Drug-induced pericarditis

Štefan Alušík^a, Zoltán Paluch^{b, c}

^a Department of Internal Medicine, Postgraduate School of Medicine, Prague

^b Department of Clinical Pharmacology and Pharmacy, General University Hospital, Prague

^c St. Elizabeth University of Health and Social Work, St. J. N. Neumann Institute, Příbram

Though not common, drug-induced pericarditis is a serious condition, since pericardial tamponade, should it develop, may be life-threatening. As the number of drugs is constantly expanding, so does the proportion of those capable of causing pericarditis. The authors reviewed the relevant literature in the PubMed database and complemented it with information from the VigiBase database. In their article, the authors present current knowledge about the mechanisms of origin and level of risk of drug-induced pericarditis and discuss relevant information on individual drugs divided into 7 classes. Some medicines are associated with a high risk of developing pericarditis, a fact to be taken into account when treating patients with these agents.

Keywords: Ceritinib, Clofarabine, Clozapine, Dasatinib, Drug-induced pericarditis, Pentostatin, Sulfasalazine

Received: March 14, 2022; Revised: March 14, 2022; Accepted: April 27, 2022; Published: December 15, 2022  Show citation