Cor Vasa 2020, 62(6):610-615 | DOI: 10.33678/cor.2020.102

A review of cardiac involvement in COVID-19 infection

Zeinab Mohseni Afshara, Arefeh Babazadehb, Mostafa Javanianb, Elham Ramezanic, Reyhaneh Shemshadid, Soheil Ebrahimpourb
a Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
b Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R., Iran
c Department of Cardiology, Kermanshah University of Medical Sciences, Kermanshah, Iran
d Kermanshah University of Medical Sciences, Kermanshah, Iran

The novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a public health emergency of international concern (PHEIC). Some studies reported SARS-CoV-2 may result in cardiovascular complications such as myocarditis, myocardial injury, acute myocardial infarction, arrhythmia, heart failure, and cardiomyopathy. It has been shown that COVID-19 patients with pre-existing medical conditions, such as heart disease, are at higher risk of increased mortality. Physicians should be well aware of cardiovascular complications when examining and treating patients with COVID-19 infection. Therefore, the current review assesses cardiovascular complications in COVID-19.

Keywords: Cardiac care, Cardiac involvement, COVID-19, Precaution

Received: August 31, 2020; Revised: August 31, 2020; Accepted: July 18, 2020; Published: December 11, 2020  Show citation

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Afshar ZM, Babazadeh A, Javanian M, Ramezani E, Shemshadi R, Ebrahimpour S. A review of cardiac involvement in COVID-19 infection. Cor Vasa. 2020;62(6):610-615. doi: 10.33678/cor.2020.102.
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    References

    1. Javanian M, Bayani M, Shokri M, et al. Clinical and laboratory findings from patients with COVID-19 pneumonia in Babol North of Iran: a retrospective cohort study. Rom J Intern Med 2020;58:161-167. Go to original source... Go to PubMed...
    2. Long B, Brady WJ, Koyfman A, Gottlieb M. Cardiovascular complications in COVID-19. Am J Emerg Med 2020;38:1504-1507. Go to original source... Go to PubMed...
    3. Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nature Reviews Cardiology 2020;17:259-260. Go to original source... Go to PubMed...
    4. Böhm M, Frey N, Giannitsis E, et al. Coronavirus Disease 2019 (COVID-19) and its implications for cardiovascular care: expert document from the German Cardiac Society and the World Heart Federation. Clin Res Cardiol 2020;109:1446-1459. Go to original source... Go to PubMed...
    5. Kumar S, Haqqani H, Wynn G, et al. Position Statement on the Management of Cardiac Electrophysiology and Cardiac Implantable Electronic Devices in Australia during the COVID-19 Pandemic: A Living Document. Heart Lung Circ 2020;29:e57-e68. Go to original source... Go to PubMed...
    6. Guzik TJ, Mohiddin SA, Dimarco A, et al. COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovasc Res 2020;116:1666-1687. Go to original source... Go to PubMed...
    7. Wu C, Chen X, Cai Y, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med 2020;180:934-943. Go to original source... Go to PubMed...
    8. Juusela A, Nazir M, Gimovsky M. Two Cases of COVID-19 Related Cardiomyopathy in Pregnancy. Am J Obstet Gynecol MFM 2020;2:100113. Go to original source... Go to PubMed...
    9. Bansal M. Cardiovascular disease and COVID-19. Diabetes Metab Syndr 2020;14:247-250. Go to original source... Go to PubMed...
    10. Siripanthong B, Nazarian S, Muser D, et al. Recognizing COVID-19-related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management. Heart Rhythm 2020;17:1463-1471. Go to original source... Go to PubMed...
    11. Deng Q, Hu B, Zhang Y, et al. Suspected myocardial injury in patients with COVID-19: Evidence from front-line clinical observation in Wuhan, China. Int J Cardiol 2020;311:116-121. Go to original source... Go to PubMed...
    12. Khayyatzadeh SS. Nutrition and Infection with COVID-19. Shahid-Sadoughi-Univ-Med-Sci 2020;5:93-96. Go to original source...
    13. Zhang L, Liu Y. Potential interventions for novel coronavirus in China: A systematic review. J Med Virol 2020;92:479-490. Go to original source... Go to PubMed...
    14. Connors JM, Levy JH. COVID-19 and its implications for thrombosis and anticoagulation. Blood 2020;135:2033-2040. Go to original source... Go to PubMed...
    15. Ponti G, Maccaferri M, Ruini C, et al. Biomarkers associated with COVID-19 disease progression. Crit Rev Clin Lab Sci 2020;57:389-399. Go to original source... Go to PubMed...
    16. Tang A, Tong ZD, Wang HL, et al. Early release - Detection of novel coronavirus By RT-PCR in stool specimen from asymptomatic child, China. Emerg Infect Dis 2020;26:1337-1339. Go to original source... Go to PubMed...
    17. Pranata R, Huang I, Lukito AA, Raharjo SB. Elevated N-terminal pro-brain natriuretic peptide is associated with increased mortality in patients with COVID-19: systematic review and meta-analysis. Postgrad Med J 2020;96:387-391. Go to original source... Go to PubMed...
    18. Gao L, Jiang D, Wen XS, et al. Prognostic value of NT-proBNP in patients with severe COVID-19. Respir Res 2020;21:83. Go to original source...
    19. Mahajan K, Negi PC, Ganju N, Asotra S. Cardiac biomarker--based risk stratification algorithm in patients with severe COVID-19. Diabetes Metab Syndr 2020;14:929-931. Go to original source... Go to PubMed...
    20. Gopinathannair R, Merchant FM, Lakkireddy DR, et al. COVID-19 and cardiac arrhythmias: a global perspective on arrhythmia characteristics and management strategies. J Interv Card Electrophysiol 2020;59:329-336. Go to original source... Go to PubMed...
    21. Kochi AN, Tagliari AP, Forleo GB, et al. Cardiac and arrhythmic complications in patients with COVID-19. J Cardiovasc Electrophysiol 2020;31:1003-1008. Go to original source... Go to PubMed...
    22. Rout A, Chan A. A Case of COVID-19 Complicated by Venous Thromboembolism Despite Being on Prophylactic Anticoagulation. J Med Cases 2020;11:189-191. Go to original source... Go to PubMed...
    23. He J, Wu B, Chen Y, et al. Characteristic ECG manifestations in patients with COVID-19. Can J Cardiol 2020;36:966.e1-966.e4. Go to original source... Go to PubMed...
    24. Wu CI, Postema PG, Arbelo E, et al. SARS-CoV-2, COVID-19, and inherited arrhythmia syndromes. Heart Rhythm 2020;17:1456-1462. Go to original source... Go to PubMed...
    25. Tsimploulis A, Rashba E, Rahman T, et al. Medication unmasked Brugada syndrome and cardiac arrest in a COVID-19 patient. HeartRhythm Case Rep 2020;6:554-557. Go to original source... Go to PubMed...
    26. Singh R, Vijayan V. Chloroquine: A Potential Drug in the COVID-19 Scenario. Trans Indian Natl Acad Eng 2020;5:399-410. Go to original source...
    27. Liu J, Cao R, Xu M, et al. Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro. Cell Discov 2020;6:16. Go to original source... Go to PubMed...
    28. Roy S, MainakMukhopadhyay. Ventricular Arrhythmia Risk Based on Ethnicity in COVID-19 Patients on Hydroxychloroquine and Azithromycin Combination: Viewpoint. SN Compr Clin Med 2020 Jun 27:1-6. Go to original source... Go to PubMed...
    29. Fatima S, Bukhari S, Pacella J. The cardiovascular implications of COVID-19: A Comprehensive Review. Medical Research Archives 2020;8(5). Go to original source...
    30. Rico-Mesa JS, White A, Anderson AS. Outcomes in Patients with COVID-19 Infection Taking ACEI/ARB. Curr Cardiol Rep 2020;22:31. Go to original source... Go to PubMed...
    31. Moore N, Carleton B, Blin P, et al. Does Ibuprofen Worsen COVID-19? Drug Saf 2020;43:611-614. Go to original source... Go to PubMed...
    32. Kutti Sridharan G, Kotagiri R, Chandiramani VH, et al. COVID-19 and Avoiding Ibuprofen. How Good Is the Evidence? Am J Ther 2020;27:e400-e402. Go to original source... Go to PubMed...
    33. Crotti L, Arbelo E. COVID-19 treatments, QT interval, and arrhythmic risk: The need for an international registry on arrhythmias. Heart Rhythm 2020;17:1423-1424. Go to original source... Go to PubMed...
    34. Schulman S. Inhibition of Warfarin Activity by Ribavirin. Ann Pharmacother 2002;36:72-74. Go to original source... Go to PubMed...
    35. Testa S, Prandoni P, Paoletti O, et al. Direct oral anticoagulant plasma levels' striking increase in severe COVID-19 respiratory syndrome patients treated with antiviral agents: The Cremona experience. J Thromb Haemost 2020;18:1320-1323. Go to original source... Go to PubMed...
    36. Askin L, Tanriverdi O, Askin HS. O Efeito da Doença de Coronavírus 2019 nas Doenças Cardiovasculares. Arq Bras Cardiol 2020;114:817-822. Go to original source... Go to PubMed...
    37. Veronese N, Demurtas J, Yang L, et al. Use of corticosteroids in coronavirus disease 2019 pneumonia: A systematic review of the literature. Front Med (Lausanne) 2020;7:170. Go to original source... Go to PubMed...
    38. Schäcke H, Döcke WD, Asadullah K. Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 2002;96:23-43. Go to original source... Go to PubMed...
    39. The European Society for Cardiology. ESC Guidance for the Diagnosis and Management of CV Disease during the COVID-19 Pandemic. https://www.escardio.org/Education/COVID-19-and-Cardiology/ESCCOVID-19-Guidance. (Last update: 10 June 2020)
    40. Lakkireddy DR, Chung MK, Gopinathannair R, et al. Guidance for Cardiac Electrophysiology During the Coronavirus (COVID-19) Pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association. Heart Rhythm 2020;17:e233-e241. Go to original source... Go to PubMed...
    41. Davis G, Adlan A. COVID-19: Impact on cardiac procedural services. 2020.
    42. Boukhris M, Hillani A, Moroni F, et al. Cardiovascular implications of the COVID-19 pandemic: a global perspective. Can J Cardiol 2020;36:1068-1080. Go to original source... Go to PubMed...
    43. Mazzone P, Peretto G, Radinovic A, et al. The COVID-19 challenge to cardiac electrophysiologists: optimizing resources at a referral center. J Interv Card Electrophysiol 2020 May 18:1-7. doi: 10.1007/s10840-020-00761-7. Epub ahead of print. PMID: 32425656; PMCID: PMC7232930. Go to original source... Go to PubMed...
    44. Matos RI, Chung KK. DoD COVID-19 Practice Management Guide: Clinical Management of COVID-19. Defense Health Agency Falls Church United States; 2020.
    45. Mahase E, Kmietowicz Z. Covid-19: doctors are told not to perform CPR on patients in cardiac arrest. BMJ 2020 Mar 29;368:m1282. Go to original source... Go to PubMed...
    46. Mahmud E, Dauerman HL, Welt FG, et al. Management of acute myocardial infarction during the COVID-19 pandemic. J Am Coll Cardiol 2020;76:1375-1384. Go to original source... Go to PubMed...
    47. Zeng J, Huang J, Pan L. How to balance acute myocardial infarction and COVID-19: the protocols from Sichuan Provincial People's Hospital. Intensive Care Med 2020;46:1111-1113. Go to original source... Go to PubMed...
    48. Luzi L, Radaelli MG. Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic. Acta Diabetol 2020;57:759-764. Go to original source... Go to PubMed...
    49. Feng S, Shen C, Xia N, et al. Rational use of face masks in the COVID-19 pandemic. Lancet Respir Med 2020;8:434-436. Go to original source... Go to PubMed...
    50. Güner R, Hasanoğlu I, Aktaş F. COVID-19: Prevention and control measures in community. Turk J Med Sci 2020;50:571-577. Go to original source... Go to PubMed...
    51. McAleer M. Prevention is better than the cure: Risk management of COVID-19. J Risk Financial Manag 2020;13:46. Go to original source...
    52. Singhvi A, Barghash M, Lala A, et al. Challenges in Heart Transplantation during COVID-19: A Single Center Experience. J Heart Lung Transplant 2020;39:894-903. Go to original source... Go to PubMed...
    53. Holzhauser L, Lourenco L, Sarswat N, et al. Early experience of COVID-19 in 2 heart transplant recipients: Case reports and review of treatment options. Am J Transplant 2020;20:2916-2922. Go to original source... Go to PubMed...
    54. DeFilippis EM, Farr MA, Givertz MM. Challenges in Heart Transplantation in the Era of COVID-19. Circulation 2020;141:2048-2051. Go to original source... Go to PubMed...
    55. Zhang H, Dai H, Xie X. Solid Organ Transplantation During the COVID-19 Pandemic. Front Immunol 2020;11:1392. Go to original source... Go to PubMed...
    56. Chen CY, Chen SF, Hollander SA, et al. Donor heart selection during the COVID-19 pandemic: a case study. J Heart Lung Transplant 2020;39:497-498. Go to original source... Go to PubMed...

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