Cor Vasa 2020, 62(5):479-482 | DOI: 10.33678/cor.2020.026
Sacubitril/Valsartan and implantable cardioverter- -defibrillators: evolving therapeutic strategies. A case report
- a Department of Clinical and Experimental Medicine, University of Messina, Italy
- b Operative Unit of ICCU and Cardiology, Hospital "Madonna del Soccorso", ASUR Marche - Area Vasta 5, San Benedetto del Tronto, Italy
- c Operative Unit of ICCU and Cardiology, Hospital "S. Maria della Misericordia", ASUR Marche - Area Vasta 1, Urbino, Italy
Heart failure is a major public health concern, being one of the most common reasons for hospitalization. Its prognosis is poor and the optimal management to date represents a continuous challenge. This case report describes a 67-year-old man with chronic heart failure with reduced ejection fraction (HFrEF), remaining symptomatic despite optimal medical therapy and refusing an implantable cardioverter-defibrillator (ICD) as a prevention for sudden cardiac death. We introduced Sacubitril/Valsartan and after 3 months of treatment we observed a significant improvement in symptoms with reduction of arrhythmic burden and, after six months even of echocardiographic parameters, leading to withdraw the indication to the ICD.
Keywords: ARNI, Cardiac implantable electronic devices, Heart failure, ICD, Sacubitril/Valsartan
Received: April 8, 2020; Revised: April 8, 2020; Accepted: April 14, 2020; Published: November 1, 2020 Show citation
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